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We further compared the upregulated genes that were annotated as pathogen-responsive (based on WormCat 38 ) among the three sterile mutants and observed a significant overlap, where the changes in fem-3(-) represented a subset of those changed in glp-1(-) mutant (Supplementary Fig

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Moreover, the modulation of IMSlocalized redox pathways did not result in large changes in steadystate E GSH [IMS] or in the recovery kinetics following diamide washout (Supplementary Figures S4S8), except for the AntA treatment of glycerolgrown cells that affected the lag phase of recovery in cytosol, matrix and IMS alike

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